This book contains a series of contributions from internationally renowned academics with special expertise in one or other diseases which collectively are grouped under the heading myeloproliferative disorders. For the editors this term includes Ph-positive chronic myeloid leukemia but also the various Ph-negative variants, some of which provide fascinating insights into the molecular mechanisms of leukemia. There have been many recent developments in understanding the Pathophysiology and a number of therapeutic innovations in this area. One particular merit of this book is the speed with which it has been produced – an important factor in this very rapidly moving field.