Applied mathematicians are becoming increasingly involved in the modeling and simulation of tumor growth, reducing the amount of experimentation necessary for drug and therapy development and shedding light on aspects of cancer dynamics that are difficult to assess experimentally. This collection of selected chapters offers a comprehensive overview of state-of-the-art mathematical methods and tools for modeling and analyzing cancer phenomena. Topics covered include stochastic evolutionary models of cancer initiation and progression, tumor cords and their response to anticancer agents, and immune competition in tumor progression and prevention. This book is an excellent reference guide for applied mathematicians, physicists, biologists, and economists interested in the modeling of complex social systems and living matter.