This book represents the conference papers of the CIRP International Conference on Manufacturing Systems 2010 and represents the theoretical and practical state of knowledge concerning the main conference topic “Sustainable Production and Logistics in Global Networks”. It includes two key-note papers by Prof. H. ElMaraghy – “Manufacturing Systems Sustainability Through Perfect Co-evolution” – and Prof. H.-P. Wiendahl – “Should CIRP develop a Production Theory?”. The included papers are dealing with a broad range of topics such as Production & logistic networks, Sustainability, Product and service development/management – (special session: IPS²), Production systems (including special session: SPECIES), Lean Engineering & Assembly, Technology in production & logistics, Knowledge management in production & logistics, Process modelling and process planning, Factory planning, Production planning, Total Quality Assurance, Productive Maintenance, ICT in production & logistics.