Cultural managers are increasingly engaged in international projects; they work in international art festivals, global companies of the creative industries, or international tourism. They are involved in cultural diplomacy and cultural development cooperation; and moreover, in times of an increasing worldwide migration, cultural managers are engaged in moderating “intercultural” change management processes in their own countries. How is internationalization influencing cultural management? Is there a tendency towards harmonization of management practices due to cultural globalization? How do cultural managers from different world regions describe their working conditions also in terms of cultural policy, and which differences can be observed? What are the main challenges of international cultural cooperation, which competencies are needed for working in international and intercultural contexts, and which training concepts in international cultural management proved to be successful? These questions are investigated on the basis of a world wide survey of cultural managers.