In this completely revised new edition of the standard work, all practice-relevant knowledge on the use of hyaluronic acid fillers in dermato-aesthetics is conveyed according to the latest science and practice. The expanded foundational section presents the latest insights into facial anatomy and its age-related changes in a uniquely vivid manner. Injection techniques have been updated and supplemented with new techniques for forehead volume, temple volumisation, eyebrow lifting, infraorbital corrections, lip white-roll and red-roll treatment and chin, chin-jaw line and neck elastosis. The topic of side-effect management has been expanded with a section on the use of hyaluronidase for their effective treatment. A new section also addresses marketing, regulations and legal frameworks in the field of aesthetics. The practical section provides detailed guidance on all aspects of treatment, illustrated with photos, drawings and clear tables. A highlight remains the updated „Filler Navigator“ as a decision-making aid for indication-specific product selection. A particular focus is the detailed presentation of individual applications, demonstrated step by step for all facial regions and indications through high-quality photos, anatomical illustrations, and, as a new feature, QR codes linking to embedded video sequences. Classical treatment methods are discussed alongside the innovative developments of recent years. For the first time, the authors describe their holistic treatment approach, minimally invasive augmentation surgery, which synthesises current techniques and possibilities with hyaluronic acid fillers. New authentic case studies convey an impression of the benefits and effectiveness of the method and, for the first time, demonstrate the potential long-term improvements achievable with hyaluronic acid therapy.