As accelerating disruption and Artificial Intelligence redefine the global economy, this vital anthology systematises cutting-edge qualitative and quantitative approaches to monitor the profound transformation of occupations, job roles, and skills. Bringing together the collective expertise of 38 authors from the European Network on Regional Labour Market Monitoring (EN RLMM), this volume bridges the gap between traditional statistical metrics and real-time, granular demands. Together, their contributions provide an indispensable framework for observing rapid changes in regional and local labour markets – equipping researchers and policy-makers with the strategic foresight needed to navigate the contemporary professional world.