The 4th Symposium on Management of Future Motorway and Urban Traffic Systems (MFTS) was held in Dresden, Germany, from November 30th to December 2nd, 2022. Organized by the Chair of Traffic Process Automation (VPA) at the “Friedrich List” Faculty of Transport and Traffic Sciences of the TU Dresden, the proceedings of this conference are published as volume 9 in the Chair’s publication series “Verkehrstelematik” and contain a large part of the presented conference extended abstracts. The focus of the MFTS conference 2022 was cooperative management of multimodal transport and reflected the vision of the professorship to be an internationally recognized group in ITS research and education with the goal of optimizing the operation of multimodal transport systems. In 14 MFTS sessions, current topics in demand and traffic management, traffic control in conventional, connected and automated transport, connected and autonomous vehicles, traffic flow modeling and simulation, new and shared mobility systems, digitization, and user behavior and safety were discussed. In addition, special sessions were organized, for example on “Human aspects in traffic modeling and simulation” and “Lesson learned from Covid19 pandemic”, whose descriptions and analyses are also included in these proceedings.