This book presents selected papers from International Conference on Sustainable Computing and Intelligent Systems (SCIS 2025), held on 7–8 November 2025, in University of Canberra, Bruce, Australia. The topics covered in the book are green computing, renewable energy integration, sustainable urban computing, IoT and sustainability, sustainable IoT applications, data analytics for sustainability, internet of things, information security, embedded systems, real-time systems, cloud computing, big data analysis, quantum computing, automation systems, intelligent IoT eHealth, bio-inspired intelligence, brain modeling and simulation, cognitive systems, cyber-physical systems, data analytics, data/web mining, data science, hybrid systems and intelligence for security.